This is referenced here:
https://cust35.myfootballnow.com/community/thread/6/1735?page=1#10587

In CUST21, I think I played with the fatigue settings. I know they were rolled back, but my RB carries have been crazy since. It's the playoffs and I can't get the best player on my team the ball so would appreciate a quick fix.

Carry distribution in the 2 games before the change:
RB1 25, RB2 14, FB1 3
RB1 19, RB2 8, FB1&2 3 total

Carry distribution since, with only minor tweaks to my offense settings and no injuries:
5 active RB/FB: 8, 8, 8, 6, 7
4 active RB/FB: 8, 4, 8, 5
5 active RB/FB: 7, 5, 4, 1, 4
4 active RB/FB: 8, 8, 8, 7

It's like the logic is trying to get active back the same carries! My FB2 in last night's got 7 carries on plays were the FB is supposed to block and the HB gets the ball. So if the 3 players ahead of him are all unavailable and he's getting the ball...I don't want to think about who is playing FB! ;)

Help JDB!

I've run a script to fix the corrupted settings. I would advise everyone to check their fatigue settings just to make sure they are where they want them to be.

How I fixed this manually in the leagues that it happened to me was to manually reset my fatigue settings.

Thank you!